Alkiviadis Tsamis


Alkiviadis Tsamis



Assistant Professor



University of Western Macedonia

Department of Mechanical Engineering {} 

Polytechnic School Campus

Office ΓΠ2_24,

Active Urban Planning Zone (ZEP)

50100 Kozani



Contact Data

Tel (office): +30 2461056689



2010 PhD in Biotechnology and Bioengineering

2004 Mechanical Engineer


Research Interests

Mechanics and engineering of soft biological materials

Role of micro-structure on the mechanical response of soft biological materials

Experimental and computational bioengineering

Mechanics and modelling at multiple time/length scales

Fluorescence imaging

Characterisation of extracellular matrix (ECM) micro-/nano-environment

Micro-/nano-fabrication technologies

ECM-based biosensors


Curriculum Vitae

Alkiviadis Tsamis was born in 1979 in Athens. He is an Assistant Professor at the Department of Mechanical Engineering of the University of Western Macedonia (Kozani, Greece). Prior to that, he was a Lecturer at University of Leicester’s School of Engineering and Postdoctoral Research Fellow at Carnegie Mellon University’s Department of Biomedical Engineering. Also, he was a Postdoctoral Research Scholar at University of Pittsburgh’s Department of Bioengineering and Postdoctoral Research Fellow at Stanford University’s Department of Mechanical Engineering under a fellowship by the Swiss National Science Foundation. He completed his Ph.D. in Biotechnology and Bioengineering at École Polytechnique Fédérale de Lausanne and obtained a Diploma in Mechanical Engineering from the National Technical University of Athens. His work has been published in a variety of journals, including Nature Communications, Materials Science and Engineering, Aging Cell, Journal of Thoracic and Cardiovascular Surgery, Journal of the Mechanical Behavior of Biomedical Materials, Journal of Biomechanics, and American Journal of Physiology. His research focuses on integration of multi-scale experimental and computational techniques to investigate structural mechanisms which are indicative of development of damage in fibre-reinforced soft biological materials.

Full CV


Course Catalogue

Engineering Statics

Strength of Materials

Biomedical Engineering

Additive Manufacturing Techniques

Tissue Biomechanics (Postgraduate)


Publications in


Google Scholar




Tsamis A. “Microstructure-based engineering of soft biological materials.” Advanced Technologies and Materials 47(2): 1-7, 11/2022.

Liyanage L, Musto L, Budgeon C, Rutty G, Biggs M, Saratzis A, Vorp DA, Vavourakis V, Bown M, Tsamis A. “Multimodal structural analysis of the human aorta: from valve to bifurcation.” European Journal of Vascular and Endovascular Surgery 63(5): 721-730, 05/2022.

Campbell J, Siddiqui S, Gill S, Tsamis A. “Internal pressure driven finite element model of a single pulmonary acinus.” MATEC Web of Conferences 349: 03008, 11/2021.

Shiwarski DJ, Tashman JW, Tsamis A, Bliley JM, Blundon MA, Aranda-Michel E, Jallerat Q, Szymanski JM, McCartney BM, Feinberg AW. “Fibronectin-based nanomechanical biosensors to map 3D surface strains in live cells and tissue.” Nature Communications 11(1): 5883, 12/2020.

Karagiorgis S, Tsamis A, Voutouri C, Turcu R, Porav SA, Socoliuc V, Vekas L, Louca M, Stylianopoulos T, Vavourakis V, Krasia-Christoforou T. “Engineered magnetoactive collagen hydrogels with tunable and predictable mechanical response.” Materials Science & Engineering C 114: 111089, 09/2020.

Wang X, Li B, Wu YP, Tsamis A, Yu HG, Liu S, Zhao J, Li YS, Li DS. “Investigation on the component evolution of a tetranuclear nickel-cluster-based Metal-Organic Framework in an electrochemical oxidation reaction.” Inorganic Chemistry 59(7): 4764-4771, 03/2020.

Stearns-Reider KM, D’Amore A, Beezhold K, Rothrauff B, Cavalli L, Wagner WR, Vorp DA, Tsamis A, Shinde S, Zhang C, Barchowsky A, Rando TA, Tuan R, Ambrosio F. “Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion.” Aging Cell 16(3): 518-528, 06/2017. (Aging Cell’s Best Paper 2017)

Tsamis A, Phillippi JA, Koch RG, Krawiec JT, D’Amore A, Watkins SC, Wagner WR, Vorp DA, Gleason TG. “Extracellular matrix fiber microarchitecture is region-specific in bicuspid aortic valve-associated ascending aortopathy.” The Journal of Thoracic and Cardiovascular Surgery 151: 1718-1728.e5, 06/2016.

Tsamis A, Pocivavsek L, Vorp DA. “Elasticity and geometry: a computational model of the Heineke-Mikulicz strictureplasty.” Biomechanics and Modeling in Mechanobiology 13(6): 1185-1198, 11/2014.

Koch RG, Tsamis A [co-first author], D’Amore A, Wagner WR, Watkins SC, Gleason TG, Vorp DA. “A custom image-based analysis tool for quantifying elastin and collagen micro-architecture in the wall of the human aorta from multi-photon microscopy.” Journal of Biomechanics 47(5): 935-943, 03/2014.

Tsamis A, Cheng A, Nguyen TC, Langer F, Miller DC, Kuhl E. “Kinematics of cardiac growth: In vivo characterization of growth tensors and strains.” Journal of the Mechanical Behavior of Biomedical Materials 8(1): 165-177, 04/2012.

Tsamis A, Rachev A, Stergiopulos N. “A Constituent-based model of age-related changes in conduit arteries.” American Journal of Physiology – Heart and Circulatory Physiology 301(4): H1286-H1301, 10/2011.

Tsamis A, Stergiopulos N. “Arterial remodeling in response to hypertension using a constituent-based model.” American Journal of Physiology – Heart and Circulatory Physiology 293(5): H3130-H3139, 11/2007.

Papadopoulos E, Tsamis A, Vlachos K. “A real-time graphic environment for a urological operation training simulator.” IEEE Transactions on Robotics and Automation 2(WE‐12): 1295-1300, 04/2004. (Award for Publication of Novel Scientific Project).